When is BNP released in the body?

B-type natriuretic peptide (BNP) is a hormone produced by the heart's ventricles in response to increased intravascular volume, particularly when there is an overload of fluid in the body. When the heart is stretched due to this excess volume, BNP is released as a compensatory mechanism to counteract the overload. It promotes diuresis, natriuresis, and vasodilation, which help to reduce blood volume and lower blood pressure, ultimately alleviating stress on the heart.

In cases where the body is experiencing high blood volume, the release of BNP indicates that the heart is working to manage the load, serving as a marker for conditions such as heart failure. This response helps healthcare providers assess and manage patients effectively, allowing for appropriate interventions based on the levels of BNP present in the bloodstream.