What is the cerebral perfusion pressure (CPP) range that must be maintained for autoregulation?

Cerebral perfusion pressure (CPP) is a critical parameter that indicates the adequacy of blood flow to the brain. Maintaining an appropriate CPP is essential for ensuring that the brain receives sufficient oxygen and nutrients, particularly during periods of stress or injury. The typical range for CPP that assures adequate autoregulation is between 50 to 150 mm Hg. Within this range, cerebral blood vessels can effectively dilate or constrict to maintain constant blood flow despite changes in systemic blood pressure.

When CPP falls below this range, there may be inadequate perfusion of brain tissues, leading to potential ischemic injury. Conversely, if CPP rises significantly above this range, it may lead to excessive cerebral blood flow, potentially resulting in cerebral edema or other complications. Therefore, the correct answer reflects the crucial range necessary for maintaining effective cerebral autoregulation and ensuring adequate cerebral blood flow.